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Mikhail Wolfson
Cambridge, MA
Graduate Researcher, Massachusetts Institute of Technology
Biotech
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Groups (10)

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Top Ideas

  • 1
    The same ideas that motiviate coworking should be applied to grad students writing papers and theses. I started a student group at the Department of Chemistry to do just that.

    10 weeks ago

  •  
    2
    All graduate students in the hard sciences should learn how to program with basic competency by the end of their first year.

    32 weeks ago

View All Top Ideas

About Me

I've been curious about science, programming, and building things my whole life. I've been a programmer since age 10, and devoted my education to computers and science. Now I want to write software and solve technical problems that really change the world for the better.

Work History

  • Massachusetts Institute of Tech. Lab for Computational Immunology
  • Doctoral Student Researcher
  • September 2006 to Present
  • * Currently constructing low-dimensional regression models of complex immunological phenomena and writing model simulations
    * Frequently build utilities in Python, Perl and shell scripts to automate research tasks
    * Release utilities to other scientists; maintain and improve them from feedback
    * Responsible for system administration of 600-core $285,000 Beowulf cluster
    * Studied the impact of peptide sequence on TCR/antigen
    complex with molecular dynamics simulations; published in Journal of Physical Chemistry (http://dx.doi.org/10.1021/jp202471d)
    * Developed C++ Monte Carlo simulations to search for macrostructure formation on T cell surfaces
    * Implemented hydrogen-bonding functionality in the PL statistical potential library using C++

  • The MathWorks, Inc
  • Statistical Software Development Intern
  • July 2011 to August 2011
  • * Comprehensively researched and implemented Burr Type XII probability
    distribution in Matlab
    * Integrated contributions into consumer product
    * Increased relative accuracy of Burr probabilities by a factor of two through
    analytical approximation
    * Presented and defended design before 5-person
    development team and head of statistical development
    * Contributions to be incorporated into next release, to be used by thousands
    of customers

  • Addgene, Inc
  • Part-time Developer
  • January 2011 to June 2011
  • * Implemented an improved BLAT-like plasmid sequence feature detection
    algorithm web application in Python and Django
    * Developed interactive AJAX library for plasmid feature visualization
    and analysis, using the Raphaëljs and jQuery JavaScript frameworks
    * Became functionally proficient in new languages (JavaScript) and technologies
    (Django) within one week
    * Contributions incorporated into the website, used by thousands of biology
    laboratories worldwide (http://addgene.org/browse/sequence/6807/)

  • Massachusetts Institute of Tech. Dept. of Chemistry
  • Graduate Student Teaching Assistant
  • September 2006 to December 2008
  • * Led discussion sections in general chemistry, thermodynamics, and
    graduate-level statistical mechanics courses
    * Independently created, solved, and taught Matlab Monte Carlo simulation project
    to introduce chemistry graduate students to stochastic simulation
    * Tutored individual students on specific issues, from programming to mathematical
    techniques

Education

  • Massachusetts Institute of Technology
  • Ph. D., Chemistry (Computational Biology)
  • 2006 - 2012
  • * Graduate-level coursework: biophysics, statistical mechanics, and quantum mechanics
    * GPA: 4.9/5.0

  • University of Wisconsin—Madison
  • B. S., Computer Science, Chemistry
  • 2002 - 2006
  • * Comprehensive Honors in the chemistry major and the liberal arts
    * GPA: 3.5/4.0
    * Computer science coursework included:
    - data structures, discrete math
    - assembly programming, digital circuit design
    - artificial intelligence, algorithmic analysis, and operating systems
    - numerical methods, advanced numberical methods

Interests
Sailing
Goals
  1. To employ my diverse computational and scientific background to develop software and solve real-worl
Specialties
Statistical Modeling, Molecular Dynamics, Linux, Shell Scripting, Matlab, LaTeX

Groups (10)

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